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| Hormone pattern in pharmacologically feminized male transsexuals in the California State prison system. |
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| TS-Si Research Service | |||||
| Saturday, 16 May 2009 06:58 | |||||
Hormone pattern in pharmacologically feminized male transsexuals in the California State prison system. J Natl Med Assoc. 1992 Mar;84(3):241-50 Authors: Valenta LJ, Elias AN, Domurat ES The hormonal profile of 40 transsexual inmates from a pool of 86 inmates in the California State prison system was studied before and after therapy with feminizing hormones. Clinical and social data were obtained on all 86 inmates; the incidence of human immunodeficiency virus (HIV) seropositivity was examined in 76 of the 86 individuals. Despite similar degrees of feminization in all 40 individuals in whom hormonal studies were performed, variable suppression of serum testosterone concentrations was present. Based on their testosterone concentrations while on feminizing hormone therapy, the transsexual inmates could be divided into three groups. In Group I (the "suppressed" group), the serum testosterone concentrations were markedly depressed (less than 10 ng/dL); in Group II (the "non-suppressed" group), the values of testosterone were normal (446 to 1072 ng/dL); and in Group III (the "intermediate" group), the testosterone values were between those of the suppressed group and the nonsuppressed group. We speculate that feminizing hormone therapy may induce the development of a state of target hormone resistance to testosterone that results in similar degrees of feminization independent of the circulating concentrations of testosterone. The incidence of HIV seropositivity (3/76) was considerably less than anticipated based on previous studies in populations at high risk for developing the acquired immunodeficiency syndrome. PMID: 1578499 [PubMed - indexed for MEDLINE]  The TS-Si Research Service consolidates information on research intiatives and findings relevant to individuals who correct the misalignment of their brains and their anatomical sex. The service tracks key scientific and medical developments at every stage of the process — from early consideration of research opportunities and published findings through practical application in clinical settings. Researchers and students from qualifying institutions regularly receive special emailings from TS-Si that consist of abstracts and other materials that support their interest areas. The TS-Si News Service is a collaborative effort by TS-Si.org editors, contributors, and corresponding institutions. The sources can include the cited individuals and organizations, as well as TS-Si.org staff contributions. Articles and news reports do not necessarily convey official positions of TS-Si, its partners, or affiliates. We welcome your comments. Use the form below to leave a public comment or send private correspondence via the TS-Si Contact Page. We will not divulge any personal details or place you on a mailing list without your permission.                      Add this page to your favorite social bookmarking websites. To create link towards this article on your website, copy and paste the text below in your page. Preview : 
Hormone pattern in pharmacologically feminized male transsexuals in the California State prison system. Saturday, 16 May 2009
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The TS-Si News Service
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are collaborations of TS-Si officials, staff, contributors, and corresponding institutions. Contents do not necessarily convey official positions of
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