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Widespread Drug-Resistant Staph Bacteria Reported in US Meat and Poultry |
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Living - Health & Fitness | |||
TS-Si News Service | |||
Saturday, 16 April 2011 09:00 | |||
Phoenix, AZ, USA. A survey of meat and poultry from U.S. grocery stores across the country shows the presence of drug-resistant strains of Staphylococcus aureus, a bacteria linked to a wide range of human diseases, in unexpectedly high rates of infection.
Proper cooking can kill staph, but it may still pose a risk to consumers through improper storage, food handling, and cross-contamination in their kitchens. This article presents the facts from the survey. The data and analysis comes from a nationwide study by the Translational Genomics Research Institute (TGen) a non-profit biomedical research institute. This is the first national assessment of antibiotic resistant S. aureus in the U.S. food supply. The data and analysis appear in the journal Clinical Infectious Diseases. Methicillin-resistant Staphylococcus aureus (MRSA) MRSA is a bacterium directly responsible for several human infections that haven proven to be very difficult to treat. The bacterium poses special difficulties in hospitals. Patients are more vulnerable to infection than the general public because of invasive devices, open wounds, and weakened immune systems. By definition, MRSA is any Staphylococcus aureus strain that resist beta-lactam antibiotics (e.g., the penicillins and cephalosporins. MRSA also is called multidrug-resistant Staphylococcus aureus or oxacillin-resistant Staphylococcus aureus (ORSA).Researchers collected and analyzed 136 samples — covering 80 brands — of beef, chicken, pork and turkey from 26 retail grocery stores in five U.S. cities: Chicago, Flagstaff, Fort Lauderdale, Los Angeles, and Washington, D.C. Nearly half of the meat and poultry samples (47 percent) were contaminated with S. aureus, and more than half of those bacteria (52 percent) were resistant to at least three classes of antibiotics. And, ![]() "For the first time, we know how much of our meat and poultry is contaminated with antibiotic-resistant Staph, and it is substantial," said Lance B. Price, Ph.D., senior author of the study and Director of TGen's Center for Food Microbiology and Environmental Health. "The fact that drug-resistant S. aureus was so prevalent, and likely came from the food animals themselves, is troubling, and demands attention to how antibiotics are used in food-animal production today," Dr. Price said. Densely-stocked industrial farms, where food animals are steadily fed low doses of antibiotics, are ideal breeding grounds for drug-resistant bacteria that move from animals to humans, the report says. "Antibiotics are the most important drugs that we have to treat Staph infections; but when Staph are resistant to three, four, five or even nine different antibiotics — like we saw in this study — that leaves physicians few options," Dr. Price said. "The emergence of antibiotic-resistant bacteria — including Staph — remains a major challenge in clinical medicine," said Paul S. Keim, Ph.D., Director of TGen's Pathogen ![]() ![]() "This study shows that much of our meat and poultry is contaminated with multidrug-resistant Staph. Now we need to determine what this means in terms of risk to the consumer," said Dr. Keim, a co-author of the paper. The U.S. government routinely surveys retail meat and poultry for four types of drug-resistant bacteria, but S. aureus is not among them. S. aureus can cause a range of illnesses from minor skin infections to life-threatening diseases, such as pneumonia, endocarditis and sepsis. The paper suggests that a more comprehensive inspection program is needed. FundingThe study was supported through a grant from The Pew Charitable Trusts as part of The Pew Campaign on Human Health and Industrial Farming.
Potential conflicts of interestL.B.P. and A.E.W. are consultants for The Pew Charitable Trusts. P.S.K. is a board member of PathoGene, LLC; is a consultant for Febits, Inc; has received grant support from the National Institutes of Health (NIH); has a patent with the Translational Genomics Research Institute (TGen); and holds stock options in Febits, Inc. PathoGene, LLC is partially owned by P.S.K. and D.M.E. All other authors: no conflicts.
TS-Si has an ongoing editorial relationship with The Pew Charitable Trusts and ![]() CitationMultidrug-Resistant Staphylococcus aureus in US Meat and Poultry. Andrew E. Waters, Tania Contente-Cuomo, Jordan Buchhagen, Cindy M. Liu, Lindsey Watson, Kimberly Pearce, Jeffrey T. Foster, Jolene Bowers, Elizabeth M. Driebe, David M. Engelthaler, Paul S. Keim, Lance B. Price. Clinical Infectious Diseases 2011; ePub ahead of print. doi:10.1093/cid/cir181.
Download PDF Abstract We characterized the prevalence, antibiotic susceptibility profiles, and genotypes of Staphylococcus aureus among US meat and poultry samples (n = 136). S. aureus contaminated 47% of samples, and multidrug resistance was common among isolates (52%). S. aureus genotypes and resistance profiles differed significantly among sample types, suggesting food animal–specific contamination. Antimicrobials are used extensively in food animal production, where they are often applied subtherapeutically for growth promotion and routine disease prevention. Surveys conducted by the National Antimicrobial Resistance Monitoring System (NARMS) indicate that retail meat and poultry products are frequently contaminated with multidrug-resistant Campylobacter species, Salmonella species, Enterococcus species, and Escherichia coli; but little is known about the prevalence of other antibiotic-resistant pathogens in the US food supply. Staphylococcus aureus is among the most prevalent causes of clinical infections globally and has garnered substantial public attention due to increasing mortality associated with multidrug resistance. A new multidrug-resistant S. aureus strain, ST398, has emerged that predominantly colonizes people working in food animal production. First discovered in 2003, ST398 now makes up a substantial proportion of the community-acquired methicillin-resistant S. aureus (MRSA) cases in the Netherlands. Multiple studies have demonstrated the high prevalence of multidrug-resistant S. aureus, including ST398, among intensively raised swine in the European Union, Canada, and the United States, but few studies have been conducted to measure its prevalence in US food products. In the current study, we evaluated the prevalence and antibiotic susceptibility profiles of S. aureus in retail meat and poultry samples from 5 US cities. We found that S. aureus contamination was common among the samples and that distinct S. aureus populations were associated with each meat and poultry type. We further demonstrated the prevalence of multidrug resistance, including resistance to clinically important antibiotics such as ciprofloxacin, quinupristin/dalfopristin, clindamycin, erythromycin, oxacillin, and daptomycin. Keywords:
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Last Updated on Friday, 15 April 2011 21:51 |