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Chad A. Mirkin, Northwestern University, George B. Rathmann Professor of Chemistry in the Weinberg College of Arts and Sciences. Photo by Bill Arsenault. 

DNA Blueprints Guide The Construction Of Specific Human Structures

Chad Mirkin discusses using DNA to build a three-dimensional structure out of gold, likening the process to building a house. Starting with basic materials such as bricks, wood, siding, stone and shingles, a construction team can build many different types of houses out of the same building blocks.
 
The article includes an audio recording of the full interview. Photo courtesy of the UCSD School of Medicine.
Media Outlets Fumble The Gene When Reporting Science News Print E-mail
Science - Genetics & Genome
TS-Si News Service   
Sunday, 07 September 2008 16:30
Jean Gene
TS-Si Genetics And Genome
Montreal, Quebec, CAN. Life on Earth didn't originate from a preexisting blueprint, but living things do have a basic architecture. Recent studies have shown that a great deal of the genome — inluding the non-coded (&q...

St. Louis, MO, USA. For years, scientists have struggled to decipher the genetic instruction book that details where and when the 20,000 genes in a human cell will be turned on or off. Different genes operate in each cell typ...

Los Angeles, CA, USA. Scientists have demonstrated for the first time the reversal of what is called epigenetic silencing, a major breakthrough in the developmental process.   Although nearly every cell in our body is ...

Edmonton, Alberta, Canada. People are different, both physically and mentally, but genetically everyone is very similar. That's been the thought of scientists for decades now. But with population research becoming more and mo...

Melbourne, Victoria, AUS. Scientists have identified a significant DNA variation that they say could result in a genetic link between reduced testosterone action and male-to-female (MtF) transsexualism (progressively known as...
Oslo, Norway. Ask this basic question to the next 10 people you meet at random: What is a gene? Chances are that most of the answers will either reflect a dated understanding of science or ignore science altogether. It comes as no surprise that media outlets fumble the subject when faced with science news, using various ways to frame the concept of a gene.
 
The scientific definition of a gene is subject to nuance, depending on the context, but does have a specific and unifying undercurrent. Simply put, a "gene is a packet of information located in a region of the genome that corresponds to a unit of inheritance (but not the totality of inheritance …)". [C1] The totality of inheritance depends on DNA in various forms and combinations. [C2] 
 

Frame that gene. A tool for analysing and classifying the communication of genetics to the public. Rebecca Carver, Ragnar Waldahl & Jarle Breivik. EMBO reports 9(10) October 2008. doi: 10.1038 / embor.2008.176 ISSN 1469-221x.

 
However, a new study that appears in EMBO reports examines newspaper reports from two highly literate democracies, the United Kingsom and Norway, finding that scientific literacy is still an elusive quality. The researchers were a molecular biologist, a media expert and a PhD student in science communication from the University of Oslo (Norway). 
 
"The common understanding of scientific topics is increasingly important because the public is more and more able to influence policy-making on scientific issues and thus the funding and even the nature of research itself", explained Rebecca Carver from the Institute of Basic Medical Sciences (IMB) at the University of Oslo and the first author of the study.
 
The study, Frame that gene [C3], is based on the analysis of 300 articles in British and Norwegian newspapers: The Guardian, The Sun and The Daily Mail (UK); and Aftenposten, Dagbladet, and VG (Norway).
 
The analysis shows that journalists present the term 'gene' — either consciously or subconsciously — using a number of different frames that may invoke various prejudiced images in the reader's mind. The authors identified frames of reference ("gene frames") in different types of media. For example,
  • The deterministic frame was particularly evident in tabloid media. It involves one-dimensional conclusions along the lines of "Drunk? It's in your genes".

    The authors think this may be related to the desire of journalists to sell a story by keeping it simple and accessible.
     
  • The evolutionary frame is in common use by scientists and provides more insight, but it may be difficult to communicate.
     
  • The metaphorical frame is more playful, as in statements like "Mazda has many Ford genes". 
"Such a diversity of meanings presents a key challenge to science communications, so both scientists and journalists could benefit from a clear classification of the polysemy," the paper argues. That statement alone requires further elaboration.
 
Polysemy is a fundamental concept within the social sciences (including linguistics and media studies). Derived from the Greek πολυσημεία ("multiple meaning"), it refers to the capacity for a sign (e.g., a word, phrase, etc.) or signs to have multiple meanings that occupy a large semantic field (sememes).
 
The authors hope their approach will be a useful tool for journalists and scientists to improve their explanations of genetics for a broader public audience. Ferocious debates on genetically modified crops or stem cell research illustrate the importance that genetics and molecular biology have gained in everyday life.
 


[C1] Searching For The Genomic Treasure That Is Us. Sharon Gaughan. TS-Si.org (1 August 2008). Ms. Gaughan provides an extended discussion of this subject, with reference to the seminal work of Gerstein et al on genetic definition. [C2] The article appears in Looking Glass, her regularly appearing opinion column.

[C3] What is a gene, post-ENCODE? History and updated definition. Mark B. Gerstein, Can Bruce, Joel S. Rozowsky, Deyou Zheng, Jiang Du, Jan O. Korbel, Olof Emanuelsson, Zhengdong D. Zhang, Sherman Weissman, and Michael Snyder. Genome Research 17(6) 669-681. [ Download PDF ]

[C3] Frame that gene. A tool for analysing and classifying the communication of genetics to the public. Rebecca Carver, Ragnar Waldahl & Jarle Breivik. EMBO reports 9(10) October 2008. doi: 10.1038 / embor.2008.176 ISSN 1469-221x.

 
TS-Si News ServiceThe TS-Si News Service is a collaborative effort by TS-Si.org editors, contributors, and corresponding institutions. The sources can include the cited individuals and organizations, as well as TS-Si.org staff contributions. Articles and news reports do not necessarily convey official positions of TS-Si, its partners, or affiliates. We welcome your comments. Use the form below to leave a public comment or send private correspondence via the TS-Si Contact Page. We will not divulge any personal details or place you on a mailing list without your permission.
 
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Last Updated on Sunday, 07 September 2008 09:53