Dedicated to the acceptance, medical treatment, & legal protection of individuals in the process of correcting the misalignment of their anatomical sex, & supporting their transition into society.

 
TS-Si Science Access/Neuroscience
Brain Mapping Initiative Reaches Core Of Human Brain
TS-Si News Service
Tuesday, 01 July 2008
Bloomington, IN, USA. An international team of researchers has created the first complete high-resolution map of how millions of neural fibers in the human cerebral cortex — the outer layer of the brain responsible for higher level thinking — connect and communicate. They have identified a single network core, or hub, that integrates both brain hemispheres.
The map shows a core of brain regions with highly interconnected structures (the brain "connectome"). The groundbreaking work also describes a novel application of a non-invasive technique that can be used by other scientists to continue mapping the trillions of neural connections in the brain at even greater resolution, which is becoming a new field of science ("connectomics").
A map of the human cerebral cortex identifies a single network core that could be key to the workings of both hemispheres of the brain. Image courtesy of Indiana University.

Mapping the Structural Core of Human Cerebral Cortex. Patric Hagmann, Leila Cammoun, Xavier Gigandet, Reto Meuli, Christopher J. Honey, Van J. Wedeen, Olaf Sporns. PLoS Biology 6(7) e159 doi: 10.1371 / journal.pbio.0060159 [ Download PDF ]

A map of the human cerebral cortex identifies a single network core that could be key to the workings of both hemispheres of the brain. Image courtesy of Indiana University.
Until now, scientists have mostly used functional magnetic resonance imaging (fMRI) technology to measure brain activity — locating which parts of the brain become active during perception or cognition — but there has been little understanding of the role of the underlying anatomy in generating this activity.
What is known of neural fiber connections and pathways has largely been learned from animal studies, and so far, no complete map of brain connections in the human brain exists.
Patric Hagmann.In this new study, a team of neuroimaging researchers led by Patric Hagmann used state-of-the-art diffus
Complex Synapses Drive Evolution Of The Human Brain
TS-Si News Service
Monday, 30 June 2008
Edinburgh, UK. New research into the brain puts us one step closer to understanding it's evolutionary origins and basic design principles. The findings suggest that size alone does not dictate brain power. The evolution of sophisticated molecular processing of nerve impulses allowed the development of animals with increasingly complex behaviors.
The study shows that two waves of increased sophistication in the structure of nerve junctions could have been the force that allowed complex brains - including our own - to evolve. The big building blocks evolved before big brains.

Evolutionary expansion and anatomical specialization of synapse proteome complexity. Richard D Emes, Andrew J Pocklington, Christopher N G Anderson, Alex Bayes, Mark O Collins, Catherine A Vickers, Mike D R Croning, Bilal R Malik, Jyoti S Choudhary, J Douglas Armstrong & Seth G N Grant. Nature Neuroscience 11, 799 - 806 (2008). doi: 10.1038 / nn.2135.

Current thinking suggests that the protein components of nerve connections - called synapses - are similar in most animals from humble worms to humans and that it is increase in the number of synapses in larger an
Isolating Comparable Brain Details In Straight Women And Gay Men
TS-Si News Service
Tuesday, 17 June 2008
Stockholm, Sweden. Research into the origins and activation of sexual orientation have become more rigorous with the advent of neuro-based tools and quantitative measurements. Such efforts surpass social studies that depend on everyday observation but ignore the underlying neurobiological mechanisms that underlie the observed behavior.
There are no known causal connections between Harry Benjamin Syndrome (HBS) and sexual orientation, but many social studies are based on an unproven association between the two. Quantitative research into sexual orientation has many benefits. There is potential relevance for people born with HBS since the isolation of causative factors for sexual orientation could eliminate unwarranted associations and support more focused attention to the HBS condition.

PET and MRI show differences in cerebral asymmetry and functional connectivity between homo- and heterosexual subjects. Ivanka Savic and Per Lindström. PNAS doi: 10.1073 / pnas.0801566105). [ Supporting Information PDF ]

A new study from from Sweden's Karolinska Institute (Stockholm Brain Institute) explores the biological basis for sexual orientatio
Modeling The Complex Interplay Between Mind And Body
TS-Si News Service
Monday, 16 June 2008
Vancouver, BC, CAN. Entering the world, we reach out to our environment, with a brain map of essential pathways for exploration. But what really goes on between our brains, eyes and appendages? And how do we process the information necessary to connect with our most immediate environment, ourselves?
“It is still a mystery, really,” says Pai, computer science professor at the University of British Columbia (UBC). "No one has ever completely mapped out the processes at the level of specific neurons, muscles and tendons.”

Musculotendon Simulation for Hand Animation. Shinjiro Sueda, Andrew Kaufman and Dinesh K. Pai. Proceedings of SIGGRAPH 2008: ACM Transaction on Graphics. [ Download PDF ]

Prof. Dinesh Pai researches the core principles which enable humans and robots to use sensory information as they move and interact with their environment. Such sensorimotor computation forms the bridge between abstract information processing in the human brain and the concrete reality of the physical world.
The human brain uses exteroceptive sensors (such as vision and touch) to perceive the state of its external environment. The brain uses pro
TS-Si Op-Ed Pages
 

Body Image, Women, And Facial Feminization Surgery

Full Facial Feminization (FFS)
Springfield, VA, USA. Society (the women and men around us) has always been more comfortable if its members fall within certain known, established patterns: this is how we dress, this is what we say, this is...

 
TS-Si Science Access
 

Brain Before Body: The Spemann-Mangold Experiments

Brain Before Body
Washington, DC, USA. Science shows that the human brain and central nervous system form before the remaining portions of our overall body plan. This is a central insight and the province of developmental biology, particularly embryology, which deals with the development of organs and other anatomical structures...

 
TS-Si Medicine
 

Research Shows Aging Brain Brings Benefit Of Mature Perspective

Research Shows Aging Brain Brings Benefit Of Mature Perspective.
Edmunton, Alberta, Canada. Does emotional wisdom come with age? Researchers identified brain patterns that help healthy people over the age of 60 regulate and control emotion better than younger counterparts. Two brain regions increased activity when...

 
TS-Si Policy Review
 

Worth Noting: Washington State Dems Sing A Different Tune

License Plate WTF
Washington, DC, USA. Criticism of the Washington state Democratic Party for an attack ad that linked an Italian-American politician to fictional organized crime. The Pennsylvania Senate ponders expansion of bathroom access to people with bowel disorders. North Carolina's motor vehicle department embarrassed by a sample license plate on its...

TS-Si Society
 

US State Workers Give Thanks For Thursday

Exhausting work week.
Washington, DC, USA. As fuel and energy costs continue to soar to record highs, a growing number of states are offering more of their public employees compressed workweeks to hold down states’ energy spending and give long-distance commuters some relief from paying high gas prices.
 
 
Utah Gov. Jon Huntsman...


Science Enterprise
Check Your Brain: The Microrobotic Construction Crew Cometh
Biotechnology: Public Attitudes On Stem Cell Research
TS-Si News Service
Thursday, 15 May 2008
Where Will Feeling Machines Get Their Emotions? From Us?
TS-Si News Service
Thursday, 10 April 2008
Biological Sciences
Brain Before Body: The Spemann-Mangold Experiments
TS-Si News Service
Sunday, 29 June 2008
One Controller of Cell Movement Discovered; More To Come?
TS-Si News Service
Saturday, 21 June 2008
So Biometric: Clocking You By The Way You Walk
TS-Si News Service
Thursday, 12 June 2008
Genetics and the Genome
The Evolution And Significance Of Imprinted Genes
TS-Si News Service
Tuesday, 24 June 2008
Sexual Dimorphism Signatures In The Brains Of Humans And Other Primates
New Technique Targets Specific Gene Inactivation In Embryo
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So They Say

On the other hand, life can be an endless parade of transsexual quilting bees aboard a cruise ship to disneyworld if only we let it!
 

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Zippy the Pinhead

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DSM V & Beyond

DSM-V: Annotated List Of TS-Si.org Articles. Our continuing update of articles on the coming DSM revisions.

Finding Our Way

 
Richard Smith, Editor-in-Chief, introduces Cases Journal. Dr. Smith urges all physicians to submit their case reports to the new open access Cases Journal, which publishes case reports from any area of healthcare.
 
Cases Journal will publish any case report that is understandable, ethical, authentic, and includes all essential information. A more selective companion, the Journal of Medical Case Reports, publishes original and interesting case reports that contribute significantly to medical knowledge. Article submissions are subject to potential publication by either journal. All reports will be entered in a common and open access database.
 
Video courtesy of BioMed Central.
Time 00:01:35.
 
TS-Si articles of related interest:
 
 
• Dr. Richard Smith: Why Do We Need Cases Journal?
 
• Dr. Richard Smith: The Policies Of Cases Journal
 
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