Dedicated to the acceptance, medical treatment, & legal protection of individuals in the process of correcting the misalignment of their anatomical sex, & supporting their transition into society.

 
TS-Si Medicine/Surgery
General Anesthesia Paradox: It Can Increase Post-surgical Pain
TS-Si News Service
Wednesday, 25 June 2008
Washington, DC, USA. General anesthesia puts patients into unconscious sleep so they do not feel surgical pain, but researchers say it can increase their discomfort once they wake up.
The findings provide scientific confirmation for an increasing number of anecdotal observations in clinics.
In the Proceedings of the National Academy of Sciences (PNAS), scientists report that "noxious" anesthesia drugs — which includes most of these general anesthetics - activate and then sensitize specific receptors on neurons in the peripheral nervous system. These are the sensory nerves in the inflammation and pain pathway that are not affected by general anesthesia drugs that target the central nervous system – the brain and the spinal cord.

General anesthetics activate a nociceptive ion channel to enhance pain and inflammation. José A. Matta, Paul M. Cornett, Rosa L. Miyares, Ken Abe, Niaz Sahibzada, and Gerard P. Ahern. PNAS 2008 105(25) 8784-8789. 10.1073 / pnas.0711038105 [ Supporting Info PDF ]

Gerard Ahern, Ph.D., an assistant professor in the Department of Pharmacology at GUMC, and lead investigator.Research from the Georgetown University Medical Center (GUMC) may lead to wider use of the few anesthetics that don't have this side effect, or to new developments.
"The choice of anesthetic appears to be an important determinant of post-operative pain," according to Gerard Ahern, Ph.D., an assistant professor in the GUMC Department of Pharmacology. "We hope these findings are ultimately helpful in providing more comfort to patients."
Ahern says that general anesthetics have long been known to cause irritation at the infusion site or in the airways when inhaled.
And investigators have also known that while they suppress the central nervous system, they can activate so called "pain-sensing" or nociceptive nerve cells on the peripher
Perceiving Beauty: The Importance Of Facial Aesthetics
TS-Si News Service
Sunday, 01 June 2008
New Haven and Greenwich, CT, USA. Human beings naturally wonder how others might perceive our appearance — and to what extent that might imply estimates by others of the the state of our feelings. Do the indicators suggest we are withdrawn or hostile (e.g., do we look tired or angry)? Our comfort in social situations might well depend on the answer to that question. Recent research suggests that looking tired or angry may have more to do with facial aesthetics than how we actually feel.
How a beholder's eye perceives our beauty has scientific support. This was most recently shown in a recent study pubished in Plastic and Reconstructive Surgery®, the medical journal of the American Society of Plastic Surgeons (ASPS) [1].

The Influence of Forehead, Brow, and Periorbital Aesthetics on Perceived Expression in the Youthful Face. Bianca I. Knoll, Keith J. Attkiss, John A. Persing. Plastic & Reconstructive Surgery. 121(5):1793-1802, May 2008. [ Download PDF ]

Researchers found that variations in eyebrow shape, eyelid position, and wrinkles significantly impact how your facial expressions, and subsequent mood, are perceived by others.
World's First Completely Automated Anesthesia System Underway
TS-Si News Service
Wednesday, 07 May 2008
Montreal, Quebec, CAN. Researchers performed the world’s first totally automated administration of an anesthetic. Nicknamed “McSleepy,” the new system administers drugs for general anesthesia and monitors their separate effects completely automatically, with no manual intervention. The anesthetic technique was used on a patient who underwent a partial nephrectomy, a procedure that removes a kidney tumor while leaving the non-cancerous part of the kidney intact, over a period of three hours and 30 minutes.
The work was done at McGill University and the McGill University Health Centre (MUHC). "We have been working on closed-loop systems, where drugs are administered, their effects continuously monitored, and the doses are adjusted accordingly, for the last five years,” said Dr. Thomas M. Hemmerling of McGill’s Department of Anesthesia and the Montreal General Hospital, who heads ITAG (the Intelligent Technology in Anesthesia research group), a team of anesthesiologists, biomedical scientists and engineers.
Hemmerling says to “Think of “McSleepy” as a sort of humanoid anesthesiologist that thinks like an anesthesiologist, analyses biological inform
Survey Shows 2 Year Age Increase In Cosmetic Surgery Patients
TS-Si News Service
Monday, 17 March 2008
Chicago, IL, USA. The American Academy of Cosmetic Surgery (AACS) has published the results of its 2007 Procedural Data, a survey of US-based AACS members completed in December 2007.
The annual survey shows that the average age for patients receiving invasive cosmetic surgery has increased since 2002. Through late 2007, the mean age of patients seeking the top ten most performed invasive procedures has increased by two years.
Dr. Steven Hopping, MD, AACS President.“Cosmetic surgeons are seeing anywhere between a one to three year increase in our patient’s age,” said Dr. Steven Hopping, MD, AACS President. “It appears that as baby boomers grow older, so does our clientele.”
The aging population and the baby boomers are likely to be the driving force behind these increases. Baby boomers make up approximately 28% of the national population, according to 2006 census reports. Baby boomers fall in the 42-64 age range and the average age of those receiving invasive and non-invasive procedures are 42.6 and 42.4, respectively.
The invasive procedures that have seen the largest increase include liposuction, sclerotherapy, facelift and forehead lift. Following suit with this trend,
TS-Si Op-Ed Pages
 

Body Image, Women, And Facial Feminization Surgery

Full Facial Feminization (FFS)
Springfield, VA, USA. Society (the women and men around us) has always been more comfortable if its members fall within certain known, established patterns: this is how we dress, this is what we say, this is...

 
TS-Si Science Access
 

Brain Before Body: The Spemann-Mangold Experiments

Brain Before Body
Washington, DC, USA. Science shows that the human brain and central nervous system form before the remaining portions of our overall body plan. This is a central insight and the province of developmental biology, particularly embryology, which deals with the development of organs and other anatomical structures...

 
TS-Si Medicine
 

Research Shows Aging Brain Brings Benefit Of Mature Perspective

Research Shows Aging Brain Brings Benefit Of Mature Perspective.
Edmunton, Alberta, Canada. Does emotional wisdom come with age? Researchers identified brain patterns that help healthy people over the age of 60 regulate and control emotion better than younger counterparts. Two brain regions increased activity when...

 
TS-Si Policy Review
 

Worth Noting: Washington State Dems Sing A Different Tune

License Plate WTF
Washington, DC, USA. Criticism of the Washington state Democratic Party for an attack ad that linked an Italian-American politician to fictional organized crime. The Pennsylvania Senate ponders expansion of bathroom access to people with bowel disorders. North Carolina's motor vehicle department embarrassed by a sample license plate on its...

TS-Si Society
 

US State Workers Give Thanks For Thursday

Exhausting work week.
Washington, DC, USA. As fuel and energy costs continue to soar to record highs, a growing number of states are offering more of their public employees compressed workweeks to hold down states’ energy spending and give long-distance commuters some relief from paying high gas prices.
 
 
Utah Gov. Jon Huntsman...


Medical Horizons
Reinvigorate Medicine: Why Do We Need Cases Journal?
Dr. Richard Smith
Thursday, 22 May 2008
Submission Guide: The Policies Of Cases Journal
Dr. Richard Smith
Thursday, 22 May 2008
Including Women And Gender in Disease Incidence and Treatment
Soc & Psych
Research Shows Aging Brain Brings Benefit Of Mature Perspective
DSM-V: Annotated List Of TS-Si.org Articles (Update)
Balancing Male Sexual Impatience Against Future Rewards
Food & Fitness
Yak Milk From Nepal Found To Produce Heart-healthy Cheese
Women Who Avoid Doctor Scales Increase Their Health Risks
Torrefacto-roasted Coffee Has Higher Antioxidant Properties
Hormones & Meds
The Metabolism Of Uric Acid In Transsexual Persons
TS-Si News Service
Monday, 09 June 2008
Potential Estrogen Substitute Found In Early Stage Bone Cells
A Common Herbicide Disrupts Human Hormonal Signaling
TS-Si News Service
Sunday, 11 May 2008
 
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So They Say

It is interesting that even when highly insecure individuals experience responses as a direct function of their actions, they are still relatively slow to adopt beneficial relationship choices. It is possible that insecure individuals simply do not realize the detrimental impact that their actions have on their relationships.
 

Amanda Vicary and R. Chris Fra
Choose Your Own Adventure: Attachment Dynamics in a Simulated Relationship

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DSM V & Beyond

DSM-V: Annotated List Of TS-Si.org Articles. Our continuing update of articles on the coming DSM revisions.

Finding Our Way

 
Richard Smith, Editor-in-Chief, introduces Cases Journal. Dr. Smith urges all physicians to submit their case reports to the new open access Cases Journal, which publishes case reports from any area of healthcare.
 
Cases Journal will publish any case report that is understandable, ethical, authentic, and includes all essential information. A more selective companion, the Journal of Medical Case Reports, publishes original and interesting case reports that contribute significantly to medical knowledge. Article submissions are subject to potential publication by either journal. All reports will be entered in a common and open access database.
 
Video courtesy of BioMed Central.
Time 00:01:35.
 
TS-Si articles of related interest:
 
 
• Dr. Richard Smith: Why Do We Need Cases Journal?
 
• Dr. Richard Smith: The Policies Of Cases Journal
 
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