The Human Genome And HBS: An Opportunity For Further Study

Regarding genetic anomalies

Tue, 20 May 2008 02:05:36 +0100

Welcome, Sue, and thank you for your suggestion. You said Prospective subjects should be screened for other genetic birth defects for obvious reasons. We have acted on your suggestion and included a separate statement on pre-screening criteria under Constraints (Item 3). Regards, Sharon - Sharon S. Gaughan

One thing you might consider...........

Tue, 20 May 2008 00:41:55 +0100

Prospective subjects should be screened for other genetic birth defects for obvious reasons. I did see no mention of that in the proposal. There are a siginificant number of us who were borne with other congenital birth defects that may muddy the results. - Sue

Reagarding Intersex Complications

Mon, 19 May 2008 06:35:14 +0100

Hello there, Zoe - thank you for your questions. You asked Should the study exclude those already diagnosed with Intersex conditions of known etiology? Or should they be recorded, but tagged separately? 1. The study we propose is intended as a controlled start at a more rigorous examination that quite clearly should extend to those individuals with Intersex conditions of known etiology. 2. A professional and well-executed research effort would develop a census of potential study participants. Quite naturally, suitable candidates should be recorded and tagged for consideration by the current study. Those members of the initial candidate pool who do not meet the current selection criteria should not be discarded altogether, but tagged as potential candidates for further consideration in downstream studies that build on the intial baseline. * These points were implicit in the original text. Spurred on by your questions, we have made a few minor changes to clarify our suggested approach. Regards, Sharon - Sharon S. Gaughan

Intersex Complications

Mon, 19 May 2008 00:28:36 +0100

Should the study exclude those already diagnosed with Intersex conditions of known etiology? Or should they be recorded, but tagged separately? - Zoe Brain